In the last EUSynBioSeminar of the year we are hosting Dr. Ana Zuniga, postdoctoral researcher at the Centre de Biochimie Structurale in Montpellier, France and Dr. Sarah Guiziou, postdoctoral researcher at the University of Washington, Seattle.

They will talk about their collaboration project titled "Logic circuit in living organism, from design to application" . The seminar will take place on Thursday, December 3rd, 17.00 Central European Time (GMT +1), via zoom

You can register here.

Update: Straight after the seminar, EUSynBioS President Huseyin Tas will be answering questions regarding the Steering Committee 2021 Application process!

Abstract:

Genetic programs operating in a history-dependent fashion are ubiquitous in nature and govern sophisticated processes such as development and differentiation. We developed a robust and scalable workflow for the implementation of history-dependent programs in living organisms by distributing the computational labor across a cellular population. Our design is based on standardized recombinase-driven DNA scaffolds expressing different genes according to the order of occurrence of inputs. Our integrated workflow offers a systematic implementation in living systems, due to its modularity and automated design. We are now applying these circuits to decode and recode lateral root development in plants and to engineer bacteria behavior for multiple purposes in human health. By sharing with you these preliminary data we want to demonstrate the wide range of applications that this technology can support when signal processing abilities are required.