2022 was a great year for the EUSynBioS seminars. We hosted 8 seminars on a wide range of fascinating topics relevant to the SynBio community. We covered research on CRISPR and quantification tools, Genome engineering, directed evolution, gene regulation, and biosafety. Overall, we received over 400 registrations from students, postdoctoral researchers, and industry members from across Europe and the rest of the world.